Category: VIP Receptors

Exposure to cigarette smoke is one of such major environmental risk factors associated with increased risk for PsA [122,123]. upregulated in the synovial lining layer [24]. Moreover, serum RANKL levels in PsA patients were significantly higher compared to patients with plaque psoriasis or healthy individuals [25].These data provide additional support for a central role of… Continue reading Exposure to cigarette smoke is one of such major environmental risk factors associated with increased risk for PsA [122,123]

miR-196, which is highly expressed in intestinal epithelia of patients with CD, downregulates the IRGM protective variant (c313C), but not the risk associated variant/SNP (c313T) in a tissue specific manner, highlighting the importance of target mRNA polymorphisms in miRNA mediated regulation [Brest 2011]. NOD2 analysis of NOD2 3-UTR reveals 11 putative miRNA binding sites that… Continue reading miR-196, which is highly expressed in intestinal epithelia of patients with CD, downregulates the IRGM protective variant (c313C), but not the risk associated variant/SNP (c313T) in a tissue specific manner, highlighting the importance of target mRNA polymorphisms in miRNA mediated regulation [Brest 2011]

[PMC free content] [PubMed] [CrossRef] [Google Scholar] 42. that the mice bearing JLP-silenced xenografts Prodigiosin exhibits reduced tumor volume. Analysis of the xenograft tumor tissues indicate a reduction in the levels of JLP, JNK, phosphorylated-JNK, c-Jun and phosphorylated-c-Jun in JLP-silenced xenografts, thereby correlating the attenuated JLP-JNK signaling node with suppressed tumor growth. Thus, our results… Continue reading [PMC free content] [PubMed] [CrossRef] [Google Scholar] 42